Mr Johnson has mild symptoms and will self-isolate in Downing Street.
“He was tested for coronavirus on the personal advice of England’s chief medical officer, Professor Chris Whitty,” a statement said.
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He will remain in control of the government’s dealing of the crisis, the statement added.
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“The test was carried out in No 10 by NHS staff and the result of the test was positive,” the statement added.
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“In keeping with the guidance, the Prime Minister is self-isolating in Downing Street.